Improving the Therapeutic Ratio in Head and Neck Cancer, 6 by Randall J Kimple

Grundtvig A Life Recalled, An Anthology of Biographical Source Texts.

Improving the Therapeutic Ratio in Head and Neck Cancer, 6


Improving the Therapeutic Ratio in Head and Neck Cancer, 6 Randall J Kimple

Published October 5th 2019

ISBN : 9780128178683

Hardcover

376 pages


Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic.The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance.This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites.


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